As publicações

Dada a grande e diversificada produção dos pesquisadores membros do Instituto de Investigação em Imunologia, com mais de 150 artigos publicados num intervalo de um ano (maio de 2024 a maio de 2025), listamos aqui alguns aos quais creditamos maior interesse e impacto. É digno de nota que essa lista contém 87 títulos! Todos os pesquisadores têm o link para o seu currículo Lattes disponível para os interessados em saber mais.

  • Adami FL et al. Anti-RBD IgG antibodies from endemic coronaviruses do not protect against SARS-CoV-2 infection among exposed uninfected individuals. Front Immunol. 2024 May 23;15:1396603.
  • Azevedo LG, Sosa E, de Queiroz ATL, Barral A, Wheeler RJ, Nicolás MF, Farias LP, Do Porto DF, Ramos PIP. High-throughput prioritization of target proteins for development of new antileishmanial compounds. Int J Parasitol Drugs Drug Resist. 2024 Aug;25:100538.
  • Barreto AS, de Franca MNF, Dos Reis TLDS, et al. Design and development of highly conserved, HLA-promiscuous T cell multiepitope vaccines against human visceral leishmaniasis. Front Immunol. 2025 Mar 31;16:1540537.
  • Barreto TMM, Souza RS, São Pedro RB, et al. Rare Genetic Variants of NLRP12 in Admixed Latino-American Children With SARS-CoV-2-Related Multisystem Inflammatory Syndrome. J Infect Dis. 2024 Dec 16;230(6):1400-1409.
  • Barreto-Duarte B, Villalva-Serra K, Croda J, Arcêncio RA, Maciel ELN, Andrade BB. Directly observed treatment for tuberculosis care and social support. Lancet Reg Health Am. 2025 Feb 13;43:101015.
  • Batista CHR, Smanio MCM, et al. Selective IgM deficiency: evaluation of 75 patients according to different diagnostic criteria. Immunol Res. 2024 Dec 16;73(1):15.
  • Bernardi V, Sacchetto L, et al. Yellow Fever Virus in Mosquitoes from Rainforest Bordering Manaus, Brazil, 2022. Emerg Infect Dis. 2025 Apr;31(4):851-854.
  • Brunetta HS, Jung AS, et al. IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis in brown fat. EMBO J. 2024 Nov;43(21):4870-4891.
  • Buerger V, Hadl S, et al. Safety and immunogenicity of a live-attenuated chikungunya virus vaccine in endemic areas of Brazil. Lancet Infect Dis. 2025 Jan;25(1):114-125.
  • Carmo HRP et al. Diacerein reduces inflammasome activation and SARS-CoV-2 replication. Front Pharmacol. 2024 Oct 7;15:1402032.
  • Carrara GMP, Souza-Silva GA, et al. Macrophage Protein Disulfide Isomerase Increases Infection by Leishmania amazonensis. Cell Biol Int. 2025 Apr 3.
  • Carrasco S, Liphaus BL, et al. Early neutrophil activation and NETs release in the pristane-induced lupus mice model. PLoS One. 2025 Jan 3;20(1):e0306943.
  • Carvalho MLR, Andrade CO, et al. Targeting PRC2 Enhances the Cytotoxic Capacity of Anti-CD19 CAR-T Cells Against Hematological Malignancies. Cancer Res. 2025 Feb 19.
  • Chaves YO, Gama WM, et al. Association between cytokine and increased risk of death in ART-naïve patients hospitalized with advanced HIV disease. BMC Infect Dis. 2025 Feb 9;25(1):197.
  • Commons RJ et al. Primaquine for Plasmodium vivax malaria in children. Lancet Child Adolesc Health. 2024 Nov;8(11):798-808.
  • da Cruz MGS, Dos Santos RO, et al. Impact of dengue virus infection on the cytoadherence of Plasmodium vivax-infected erythrocytes. Mem Inst Oswaldo Cruz. 2025 Apr 25;120:e240185.
  • Da Silva Filho J, Herder V, et al. A spatially resolved single-cell lung atlas distinguishes COVID-19 disease trajectories. Sci Transl Med. 2024 Sep 11;16(764):eadk9149.
  • da Silva GS, Fontenelle FA, et al. Impact of CYP2D6, MAOA, and UGT2B7 genetic variants on recurrence of Plasmodium Vivax in the Brazilian Amazon. Sci Rep. 2025 May 2;15(1):15330.
  • da Silva Pereira JA et al. LXR regulation of adipose tissue inflammation during obesity. Obesity (Silver Spring). 2025 Jan;33(1):78-90.
  • Daher IP, Almeida BDS, et al. Neutralizing antibody responses after a two-dose regimen with BNT162b2, CoronaVac or ChAdOx1-S in Brazil. Clin Immunol. 2025 Apr 2;276:110492.
  • Davanzo GG, Castelucci BG, et al. Obesity-Induced Metabolic Priming Exacerbates SARS-CoV-2 Inflammation. Immunology. 2025 Apr 23.
  • de Almeida Rodrigues MG et al. Associations between COVID-19 and Glucose-6-Phosphate Dehydrogenase Activity in Brazil. Am J Trop Med Hyg. 2024 Apr 9;110(6):1191-1197.
  • de Castro MV, Cariste LM, et al. Potential protective role of IFIT3 in COVID-19. Front Cell Infect Microbiol. 2024 Nov 27;14:1464581.
  • de Farias IS, Ribeiro G, et al. Caspase-1/11 controls Zika virus replication in astrocytes by inhibiting glycolytic metabolism. FEBS J. 2025 Mar 12.
  • De Lima Gualque MW, Vaso CO, et al. Peptides from Galleria mellonella against Cryptococcus spp. Future Microbiol. 2025 Jan;20(1):11-21.
  • de Lima VA, Nunes JPS, et al. Development of a multimeric recombinant protein to induce SARS-CoV-2 neutralization. Immun Inflamm Dis. 2024 Jul;12(7):e1353.
  • de Melo Iani FC, Pereira FM, et al. Travel-associated international spread of Oropouche virus beyond the Amazon. J Travel Med. 2025 Mar 30;32(3):taaf018.
  • de Morais Gomes V, Santos DM, et al. P.1 and P.2 SARS-CoV-2 Brazilian variants activate the unfolded protein response. J Proteomics. 2025 May 15;315:105397.
  • de Oliveira LA et al. BNT162B2 vaccine response in Brazilian adolescents. Vaccine. 2025 Jan 1;43(Pt 1):126494.
  • de Rezende DF, Garcia KKS, et al. The 1985 Plasmodium vivax malaria elimination campaign in Santa Catarina, Brazil. Malar J. 2025 Feb 21;24(1):57.
  • Duarte-Silva M et al. Leukocyte dysfunction and reduced CTLA-4 expression in perianal Crohn's disease. Clin Exp Immunol. 2024 Jun 20;217(1):78-88.
  • Ferreira CS, Da Silva AT, et al. Immune and vascular modulation by HERVs in dengue severity progression. Front Immunol. 2025 Mar 7;16:1557588.
  • Frade AF, Guérin H, Nunes JPS, et al. Cardiac and Digestive Forms of Chagas Disease: An Update. Mediators Inflamm. 2025 Apr 21;2025:8862004.
  • Freitas RCC, Bortolin RH, et al. Integrative analysis of miRNAs and proteins in plasma extracellular vesicles of patients with familial hypercholesterolemia. Clin Chim Acta. 2025 Feb 15;568:120123.
  • Gasparoto ALDB, Graeff SV, et al. Mapping the viral battlefield: SARS-CoV-2 infection dynamics among healthcare workers in Brazil. Hum Resour Health. 2025 Feb 11;23(1):8.
  • Ghezzi B, Valencia C, et al. A Methodological Approach to Measuring the Impact of TAK-003 for Dengue Prevention in Dourados, Brazil. Vaccines (Basel). 2025 Jan 25;13(2):121.
  • Giavina-Bianchi B, Giavina-Bianchi P. Rapid food desensitization associated with omalizumab before oral immunotherapy. World Allergy Organ J. 2025 Jan 28;18(2):101032.
  • Giavina-Bianchi P, Giavina-Bianchi M, Kalil J. Urticaria unveiled in hereditary angioedema with carboxypeptidase N mutation. J Allergy Clin Immunol Glob. 2025 Jan 10;4(2):100405.
  • Gomes OV et al. Chronic kidney disease prevalence among Truká Indigenous adults in Cabrobó, Brazil. Lancet Reg Health Am. 2024 Sep 26;38:100882.
  • Guimarães GR, Maklouf GR, et al. Single-cell resolution characterization of myeloid-derived cell states with implication in cancer outcome. Nat Commun. 2024 Jul 7;15(1):5694.
  • Gurgel-Gonçalves R, Oliveira WK, Croda J. The greatest Dengue epidemic in Brazil. Rev Soc Bras Med Trop. 2024 Sep 20;57:e002032024.
  • Ishak CA, Marhon SA, et al. Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion. Cancer Discov. 2025 Apr 2;15(4):793-817.
  • Joseph S, Silbiger VN, et al. Diagnostic and prognostic significance of miRNAs in arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2025 Apr 11.
  • Lacerda MVG, Bassat Q. Mapping the malaria burden in the context of a global pandemic. Lancet. 2025 Mar 22;405(10483):952-953.
  • Lazar Neto F et al. Effectiveness of the fourth dose of COVID-19 vaccines against severe COVID-19 in Brazil. Lancet Reg Health Am. 2024 May 3;34:100755.
  • Levy D, Calllera AF, et al. TNF-Alpha Inhibitor Prevents Cigarette Smoke Extract-Induced Cell Death in Osteoarthritis-Derived Chondrocytes. Cells. 2025 Mar 25;14(7):489.
  • Liu YE et al. Mass incarceration driving TB epidemic in Latin America. Lancet Public Health. 2024 Nov;9(11):e841-e851.
  • Macedo PRC, Moraes P, Arruda LK, et al. Efficacy and safety of sublingual immunotherapy for allergic rhinitis. World Allergy Organ J. 2025 Jan 28;18(2):101020.
  • Magerl M, Riedl MA, Arruda LK, et al. Global frequency, diagnosis, and treatment of hereditary angioedema with normal C1 inhibitor. J Allergy Clin Immunol Glob. 2025 Feb 27;4(3):100446.
  • Martinez EG et al. Anti-Plasmodium vivax treatment efficacy. Int J Infect Dis. 2025 Jan;150:107297.
  • McDonald E, Pittet LF, et al. Antecedent and persistent symptoms in COVID-19: Insights from the BRACE trial. J Infect. 2024 Nov;89(5):106267.
  • Messina NL, Germano S, et al. Effect of BCG vaccination on immune responses to SARS-CoV-2 and COVID-19 vaccination. Clin Transl Immunology. 2025 Jan 25;14(1):e70023.
  • Miyaji KT, Ibrahim KY, et al. Safety of CoronaVac and heterologous BNT162b2 in immunocompromised individuals. Rev Inst Med Trop Sao Paulo. 2025 Jan 20;67:e2.
  • Moreira Puga MA, Dias de Oliveira R, et al. Immunogenicity of fractional vs. full booster doses of COVID-19 vaccines in Brazil. Lancet Reg Health Am. 2025 Feb 22;44:101031.
  • Moro AM, Brucker N, et al. The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers. Biol Trace Elem Res. 2024 Dec 18.
  • Munhoz DD, Fonseca DLM, et al. Integrative immunology identified interferome signatures in uveitis. Front Immunol. 2025 Apr 9;16:1509805.
  • Murillo-Casas AD, Zwiener R, Giavina-Bianchi P, et al. Latin American guidelines for Stevens-Johnson syndrome and toxic epidermal necrolysis. World Allergy Organ J. 2025 Mar 26;18(4):101046.
  • Nicacio JM et al. Arbovirus exposure and subclinical myocardial dysfunction in Northeast Brazil's Indigenous population. BMC Infect Dis. 2025 Jan 20;25(1):89.
  • Noble CCA, McDonald E, et al. Characterising the SARS-CoV-2 nucleocapsid (N) protein antibody response. J Infect. 2025 Mar;90(3):106436.
  • Nogueira DS, Lage LAPC, et al. Clinical-Demographic Profile in Classic Follicular Lymphoma. Cancers (Basel). 2024 Nov 22;16(23):3914.
  • Nogueira ML et al. Efficacy and safety of Butantan-DV in participants aged 2-59 years: Phase 3 trial in Brazil. Lancet Infect Dis. 2024 Nov;24(11):1234-1244.
  • Nyirenda J et al. Cellular signature of fatal lung COVID-19 in Malawi. Nat Med. 2024 Dec;30(12):3765-3777.
  • Oliveira RD et al. Symptomatic disease from serotype 4 vaccine virus. Travel Med Infect Dis. 2024 Nov-Dec;62:102782.
  • Pelletier AN et al. A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine. Cell Rep. 2024 Jul 23;43(7):114370.
  • Pereira DB, Lacerda MVG, et al. An observational pilot study of an active surveillance tool to enhance pharmacovigilance in Brazil. Malar J. 2025 Mar 3;24(1):71.
  • Perez-Riverol A, Hideki Izuka Moraes G, et al. Two Novel Venom Allergens from the Social Wasp Apoica pallens. Clin Exp Allergy. 2025 Mar;55(3):250-252.
  • Queiroz JHFS et al. Seroprevalence of Treponema pallidum infection among high-risk populations from Brazil. Acta Trop. 2024 Aug;256:107255.
  • Ramos AA, Bertola L, et al. Socioeconomic determinants of cognition among older adults in Brazil. Soc Psychiatry Psychiatr Epidemiol. 2024 Jul 30.
  • Ramundo MS, da Fonseca GC, et al. Transcriptomic insights into post-chikungunya chronic inflammatory joint disease. Sci Rep. 2025 Feb 25;15(1):6745.
  • Reichert CO, Levy D, et al. PON-1 and PON-2 Polymorphisms and PON-1 Paraoxonase Activity in People Living with HIV-1. Antioxidants (Basel). 2025 Feb 12;14(2):209.
  • Reshef A, Buttgereit T, et al. Definition, acronyms, nomenclature, and classification of angioedema (DANCE). J Allergy Clin Immunol. 2024 Aug;154(2):398-411.e1.
  • Romão CM, de Lara Janz F, et al. Expression of ABCB1, ABCC1, and LRP in Mesenchymal Stem Cells. Int J Mol Sci. 2025 Jan 9;26(2):510.
  • Rouadi PW, Idriss SA, et al. WAO-ARIA consensus on chronic cough. World Allergy Organ J. 2025 Feb 24;18(3):101034.
  • Salindri AD, Bampi JVB, et al. Evaluation of an ultra-portable X-ray system for tuberculosis active case finding in prisons. Res Sq [Preprint]. 2025 Apr 7.
  • Tornimbene B, Leiva Rioja ZB, Barral-Netto M, et al. Data integration and synthesis for pandemic and epidemic intelligence. BMC Proc. 2025;19(Suppl 4):12.
  • van Lieshout Titan A, Klaassen F, et al. Cost-effectiveness of screening for M. tuberculosis infection among formerly incarcerated in Brazil. Lancet Glob Health. 2024 Sep;12(9):e1446-e1455.
  • Veras Florentino PT, Araújo VO, et al. Text mining method to unravel long COVID's clinical condition. Cell Death Dis. 2024 Sep 13;15(9):671.
  • Vieceli T et al. SARS-CoV-2, Influenza, and co-infections in Brazil. Public Health. 2025 Jan;238:101-107.
  • Villalva-Serra K, Barreto-Duarte B, et al. Impact of strategic public health interventions to reduce tuberculosis incidence in Brazil. Lancet Reg Health Am. 2024 Dec 11;41:100963.
  • Villanueva P et al. Factors influencing adverse events following COVID-19 vaccination. Hum Vaccin Immunother. 2024 Dec 31;20(1):2323853.
  • Walter KS et al. Signatures of transmission in within-host M. tuberculosis complex variation. Lancet Microbe. 2025 Jan;6(1):100936.